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Diabetes Mellitus Accelerates Cartilaginous Metaplasia and Calcification in Atherosclerotic Vessels of LDLr Mutant Mice

BACKGROUND: Vascular calcification is highly prevalent in patients with type II diabetes mellitus (T2DM). Little is known about whether T2DM is causative. METHODS: Low density lipoprotein receptor mutant (LDLr−/−) mice were fed with customized diabetogenic and/or procalcific diets to induce atherosc...

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Bibliographische Detailangaben
Hauptverfasser: Nguyen, Ngoc, Naik, Veena, Speer, Mei Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481013/
https://ncbi.nlm.nih.gov/pubmed/22818582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carpath.2012.06.007
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