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Neurovirulence of murine coronavirus JHM temperature-sensitive mutants in rats.

The murine coronavirus strain JHM is highly neurotropic in rats and has a marked tendency to cause demyelinating central nervous system diseases after intracerebral inoculation. The clinical diseases observed range from an acute encephalomyelitis occurring within 2 weeks postinfection to a subacute...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Wege, H, Koga, M, Watanabe, R, Nagashima, K, ter Meulen, V
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1983
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348101/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6301992/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.39.3.1316-1324.1983
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