IFN-γ and TNF-α induced GBP-1 inhibits epithelial cell proliferation through suppression of β-catenin/TCF signaling

Proinflammatory cytokines induce Guanylate Binding Protein 1 (GBP-1) protein expression in intestinal epithelial tissues. GBP-1 has been described as influencing a number of cellular processes important for epithelial homeostasis, including cell proliferation. However, many questions remain as to th...

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Autori principali: Capaldo, Christopher T., Beeman, Neal, Hilgarth, Roland S., Nava, Porfirio, Louis, Nancy A., Naschberger, Elisabeth, Stürzl, Michael, Parkos, Charles A., Nusrat, Asma
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481006/
https://ncbi.nlm.nih.gov/pubmed/22692453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2012.41
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