Low or undetectable TPO receptor expression in malignant tissue and cell lines derived from breast, lung, and ovarian tumors

BACKGROUND: Numerous efficacious chemotherapy regimens may cause thrombocytopenia. Thrombopoietin receptor (TPO-R) agonists, such as eltrombopag, represent a novel approach for the treatment of chemotherapy-induced thrombocytopenia. The TPO-R MPL is expressed on megakaryocytes and megakaryocyte prec...

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Detalhes bibliográficos
Main Authors: Erickson-Miller, Connie L, Pillarisetti, Kodandaram, Kirchner, Jennifer, Figueroa, David J, Ottesen, Lone, Martin, Anne-Marie, Liu, Yuan, Kamel, Yasser Mostafa, Messam, Conrad
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480928/
https://ncbi.nlm.nih.gov/pubmed/22967017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-405
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