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Improvement of Targeted Chemotherapy of HER2-positive Ovarian Malignant Cell Line by Z(HER2)-Idarubicin Conjugate: An in vitro Study

BACKGROUND & OBJECTIVE: Overexpression of human epidermal growth factor receptor 2 (HER2) causes cell transformation and development of various types of malignancies. Idarubicin is an effective anti-neoplastic drug but its specific delivery to the targeted cells is still a great challenge. Affib...

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Detalhes bibliográficos
Publicado no:Iran J Pathol
Main Authors: Siavoshinia, Leila, Jamalan, Mostafa, Zeinali, Majid, Pourshohod, Aminollah, Koushki, Mahdie, Moradipoodeh, Bahman, Mohammadzadeh, Ghorban
Formato: Artigo
Idioma:Inglês
Publicado em: Iranian Society of Pathology 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085286/
https://ncbi.nlm.nih.gov/pubmed/33936221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.30699/IJP.2020.120392.2310
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