Development of a new humanized mouse model to study acute inflammatory arthritis

BACKGROUND: Substantial advances have been generated in understanding the pathogenesis of rheumatoid arthritis (RA). Current murine models of RA-like disease have provided great insights into the molecular mechanism of inflammatory arthritis due to the use of genetically deficient or transgenic mice...

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Detalhes bibliográficos
Main Authors: Misharin, Alexander V, Haines, G Kenneth, Rose, Shawn, Gierut, Angelical K, Hotchkiss, Richard S, Perlman, Harris
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480927/
https://ncbi.nlm.nih.gov/pubmed/22974474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-10-190
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