Sequence variation does not confound the measurement of plasma PfHRP2 concentration in African children presenting with severe malaria

BACKGROUND: Plasmodium falciparum histidine-rich protein PFHRP2 measurement is used widely for diagnosis, and more recently for severity assessment in falciparum malaria. The Pfhrp2 gene is highly polymorphic, with deletion of the entire gene reported in both laboratory and field isolates. These iss...

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Detalhes bibliográficos
Main Authors: Ramutton, Thiranut, Hendriksen, Ilse CE, Mwanga-Amumpaire, Juliet, Mtove, George, Olaosebikan, Rasaq, Tshefu, Antoinette K, Onyamboko, Marie A, Karema, Corine, Maitland, Kathryn, Gomes, Ermelinda, Gesase, Samwel, Reyburn, Hugh, Silamut, Kamolrat, Chotivanich, Kesinee, Promnares, Kamoltip, Fanello, Caterina I, von Seidlein, Lorenz, Day, Nicholas PJ, White, Nicholas J, Dondorp, Arjen M, Imwong, Mallika, Woodrow, Charles J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480887/
https://ncbi.nlm.nih.gov/pubmed/22898068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-276
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