Diagnosing Severe Falciparum Malaria in Parasitaemic African Children: A Prospective Evaluation of Plasma PfHRP2 Measurement

BACKGROUND: In African children, distinguishing severe falciparum malaria from other severe febrile illnesses with coincidental Plasmodium falciparum parasitaemia is a major challenge. P. falciparum histidine-rich protein 2 (PfHRP2) is released by mature sequestered parasites and can be used to esti...

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Main Authors: Hendriksen, Ilse C. E., Mwanga-Amumpaire, Juliet, von Seidlein, Lorenz, Mtove, George, White, Lisa J., Olaosebikan, Rasaq, Lee, Sue J., Tshefu, Antoinette K., Woodrow, Charles, Amos, Ben, Karema, Corine, Saiwaew, Somporn, Maitland, Kathryn, Gomes, Ermelinda, Pan-Ngum, Wirichada, Gesase, Samwel, Silamut, Kamolrat, Reyburn, Hugh, Joseph, Sarah, Chotivanich, Kesinee, Fanello, Caterina I., Day, Nicholas P. J., White, Nicholas J., Dondorp, Arjen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424256/
https://ncbi.nlm.nih.gov/pubmed/22927801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1001297
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