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Biology and Clinical Management of Myeloproliferative Neoplasms and Development of the JAK Inhibitor Ruxolitinib

Myeloproliferative neoplasms (MPN) are debilitating stem cell-derived clonal myeloid malignancies. Conventional treatments for the BCR-ABL1-negative MPN including polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF) have, so far, been unsatisfactory. Following the...

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Bibliographic Details
Main Authors: Mascarenhas, J, Mughal, TI, Verstovsek, S
Format: Artigo
Language:Inglês
Published: Bentham Science Publishers 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480698/
https://ncbi.nlm.nih.gov/pubmed/22830345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/092986712803251511
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