Virtual Screening for Finding Novel COX-2 Inhibitors as Antitumor Agents

The cyclooxygenase-2 (COX-2) enzyme binds to arachidonic acid resulting in the release of metabolites that induce pain and inflammatory responses. Recent studies have shown that strong COX-2 expression is highly correlated with increased tumor risk. Therefore, the development of potent COX-2 inhibit...

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Autores principales: Badieyan, Zohreh S, Moallem, Seyed Adel, Mehri, Soghra, Shahsavand, Shabnam, Hadizadeh, Farzin
Formato: Artigo
Lenguaje:Inglês
Publicado: Bentham Open 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480690/
https://ncbi.nlm.nih.gov/pubmed/23115597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874104501206010015
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