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Virtual Screening for Finding Novel COX-2 Inhibitors as Antitumor Agents
The cyclooxygenase-2 (COX-2) enzyme binds to arachidonic acid resulting in the release of metabolites that induce pain and inflammatory responses. Recent studies have shown that strong COX-2 expression is highly correlated with increased tumor risk. Therefore, the development of potent COX-2 inhibit...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Bentham Open
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3480690/ https://ncbi.nlm.nih.gov/pubmed/23115597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874104501206010015 |
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