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Elevated Epidermal Thymic Stromal Lymphopoietin Levels Establish an Anti-Tumor Environment in the Skin

Thymic Stromal Lymphopoietin (TSLP), a cytokine implicated in induction of T helper 2 (Th2)-mediated allergic inflammation, has recently been shown to stimulate solid tumor growth and metastasis. Conversely, studying mice with clonal loss of Notch signaling in their skin revealed that high levels of...

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Bibliographic Details
Main Authors: Demehri, Shadmehr, Turkoz, Ahu, Manivasagam, Sindhu, Yockey, Laura J., Turkoz, Mustafa, Kopan, Raphael
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480666/
https://ncbi.nlm.nih.gov/pubmed/23079659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.08.017
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