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Mutation Analysis of BRCA1, BRCA2, PALB2 and BRD7 in a Hospital-Based Series of German Patients with Triple-Negative Breast Cancer
Triple-negative breast cancer (TNBC) is an aggressive form of breast carcinoma with a poor prognosis. Recent evidence suggests that some patients with TNBC harbour germ-line mutations in DNA repair genes which may render their tumours susceptible to novel therapies such as treatment with PARP inhibi...
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Main Authors: | , , , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
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Public Library of Science
2012
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在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3480465/ https://ncbi.nlm.nih.gov/pubmed/23110154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047993 |
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