Mutation Analysis of BRCA1, BRCA2, PALB2 and BRD7 in a Hospital-Based Series of German Patients with Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) is an aggressive form of breast carcinoma with a poor prognosis. Recent evidence suggests that some patients with TNBC harbour germ-line mutations in DNA repair genes which may render their tumours susceptible to novel therapies such as treatment with PARP inhibi...

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Detalhes bibliográficos
Main Authors: Pern, Franziska, Bogdanova, Natalia, Schürmann, Peter, Lin, Min, Ay, Aysun, Länger, Florian, Hillemanns, Peter, Christiansen, Hans, Park-Simon, Tjoung-Won, Dörk, Thilo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480465/
https://ncbi.nlm.nih.gov/pubmed/23110154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047993
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