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Characterization and Identification of Subpopulations of Mononuclear Preosteoclasts Induced by TNF-α in Combination with TGF-β in Rats

Osteoclasts are unique multinucleated cells formed by fusion of preosteoclasts derived from cells of the monocyte/macrophage lineage, which are induced by RANKL. However, characteristics and subpopulations of osteoclast precursor cells are poorly understood. We show here that a combination of TNF-α,...

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Autori principali: Matsubara, Rei, Kukita, Toshio, Ichigi, Yuka, Takigawa, Ippei, Qu, Peng-Fei, Funakubo, Noboru, Miyamoto, Hiroshi, Nonaka, Kazuaki, Kukita, Akiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480460/
https://ncbi.nlm.nih.gov/pubmed/23110133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047930
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