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Infection of RANKL-Primed RAW-D Macrophages with Porphyromonas gingivalis Promotes Osteoclastogenesis in a TNF-α-Independent Manner

Infection of macrophages with bacteria induces the production of pro-inflammatory cytokines including TNF-α. TNF-α directly stimulates osteoclast differentiation from bone marrow macrophages in vitro as well as indirectly via osteoblasts. Recently, it was reported that bacterial components such as L...

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Detalhes bibliográficos
Main Authors: Kukita, Akiko, Ichigi, Yuka, Takigawa, Ippei, Watanabe, Toshiyuki, Kukita, Toshio, Miyamoto, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377672/
https://ncbi.nlm.nih.gov/pubmed/22723864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038500
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