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Sequence-specific nucleic acid detection from binary pore conductance measurement
We describe a platform for sequence-specific nucleic acid (NA) detection utilizing a micropipette tapered to a 2 μm diameter pore and 3 μm diameter polystyrene beads to which uncharged peptide nucleic acid (PNA) probe molecules have been conjugated. As the target NAs hybridize to the complementary P...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3480342/ https://ncbi.nlm.nih.gov/pubmed/22931376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3059205 |
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