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Anticancer activity of proapoptotic peptides is highly improved by thermal targeting using elastin-like polypeptides

Inducing apoptosis in cancer cells is an effective strategy for cancer therapy. The cationic α-helix forming KLAKLAKKLAKLAK peptide (KLAK) has been known to induce apoptosis by disrupting the mitochondria. In the present study, we have designed a thermally targeted KLAK peptide by genetically engine...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Moktan, Shama, Raucher, Drazen
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480076/
https://ncbi.nlm.nih.gov/pubmed/23105921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10989-012-9295-y
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