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Anticancer activity of proapoptotic peptides is highly improved by thermal targeting using elastin-like polypeptides
Inducing apoptosis in cancer cells is an effective strategy for cancer therapy. The cationic α-helix forming KLAKLAKKLAKLAK peptide (KLAK) has been known to induce apoptosis by disrupting the mitochondria. In the present study, we have designed a thermally targeted KLAK peptide by genetically engine...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3480076/ https://ncbi.nlm.nih.gov/pubmed/23105921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10989-012-9295-y |
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