Cas5d protein processes pre-crRNA and assembles into a Cascade-like interference complex in Subtype I-C/Dvulg CRISPR-Cas system

Clustered regularly interspaced short palindromic repeats (CRISPRs), together with an operon of CRISPR-associated (Cas) proteins, form an RNA-based prokaryotic immune system against exogenous genetic elements. Cas5 family proteins are found in several Type I CRISPR-Cas systems. Here we report the mo...

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Bibliographische Detailangaben
Hauptverfasser: Nam, Ki Hyun, Haitjema, Charles, Liu, Xueqi, Ding, Fran, Wang, Hongwei, DeLisa, Matthew P., Ke, Ailong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479641/
https://ncbi.nlm.nih.gov/pubmed/22841292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.06.016
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