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Interplay between electrical activity and bone morphogenetic protein signaling regulates spinal neuron differentiation

A gradient of bone morphogenetic proteins (BMPs) along the dorsoventral axis of the spinal cord is necessary for the specification of dorsal neurons. Concurrently, a gradient of calcium-mediated electrical activity is present in the developing spinal cord but in an opposing ventrodorsal direction. W...

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Bibliografische gegevens
Hoofdauteurs: Swapna, Immani, Borodinsky, Laura N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479614/
https://ncbi.nlm.nih.gov/pubmed/22991474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202818109
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