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Interplay between electrical activity and bone morphogenetic protein signaling regulates spinal neuron differentiation
A gradient of bone morphogenetic proteins (BMPs) along the dorsoventral axis of the spinal cord is necessary for the specification of dorsal neurons. Concurrently, a gradient of calcium-mediated electrical activity is present in the developing spinal cord but in an opposing ventrodorsal direction. W...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3479614/ https://ncbi.nlm.nih.gov/pubmed/22991474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202818109 |
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