Cell-type specific deletion of GABA(A)α1 in corticotropin-releasing factor-containing neurons enhances anxiety and disrupts fear extinction

Corticotropin-releasing factor (CRF) is critical for the endocrine, autonomic, and behavioral responses to stressors, and it has been shown to modulate fear and anxiety. The CRF receptor is widely expressed across a variety of cell types, impeding progress toward understanding the contribution of sp...

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Bibliographic Details
Main Authors: Gafford, Georgette M., Guo, Ji-Dong, Flandreau, Elizabeth I., Hazra, Rimi, Rainnie, Donald G., Ressler, Kerry J.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2012
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479581/
https://ncbi.nlm.nih.gov/pubmed/22992651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119261109
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