Cell-type specific deletion of GABA(A)α1 in corticotropin-releasing factor-containing neurons enhances anxiety and disrupts fear extinction

Corticotropin-releasing factor (CRF) is critical for the endocrine, autonomic, and behavioral responses to stressors, and it has been shown to modulate fear and anxiety. The CRF receptor is widely expressed across a variety of cell types, impeding progress toward understanding the contribution of sp...

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Main Authors: Gafford, Georgette M., Guo, Ji-Dong, Flandreau, Elizabeth I., Hazra, Rimi, Rainnie, Donald G., Ressler, Kerry J.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479581/
https://ncbi.nlm.nih.gov/pubmed/22992651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119261109
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