Platelet biogenesis and functions require correct protein O-glycosylation

Platelets express a variety of membrane and secreted glycoproteins, but the importance of glycosylation to platelet functions is poorly understood. To explore the importance of O-glycosylation, we generated mice with a targeted deletion of Cosmc in murine endothelial/hematopoietic cells (EHC) (EHC C...

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Detalhes bibliográficos
Main Authors: Wang, Yingchun, Jobe, Shawn M., Ding, Xiaokun, Choo, Hyojung, Archer, David R., Mi, Rongjuan, Ju, Tongzhong, Cummings, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479543/
https://ncbi.nlm.nih.gov/pubmed/22988088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208253109
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