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A novel fluorescent assay for T-synthase activity

Loss of T-synthase (uridine diphosphate galactose:N-acetylgalactosaminyl-α1-Ser/Thr β3galactosyltransferase), a key enzyme required for the formation of mucin-type core 1 O-glycans, is observed in several human diseases, including cancer, Tn syndrome and IgA nephropathy, but current methods to assay...

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Detalhes bibliográficos
Main Authors: Ju, Tongzhong, Xia, Baoyun, Aryal, Rajindra P, Wang, Wenyi, Wang, Yingchun, Ding, Xiaokun, Mi, Rongjuan, He, Miao, Cummings, Richard D
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033746/
https://ncbi.nlm.nih.gov/pubmed/20959392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwq168
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