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Conformational state of the MscS mechanosensitive channel in solution revealed by pulsed electron–electron double resonance (PELDOR) spectroscopy

The heptameric mechanosensitive channel of small conductance (MscS) provides a critical function in Escherichia coli where it opens in response to increased bilayer tension. Three approaches have defined different closed and open structures of the channel, resulting in mutually incompatible models o...

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Detalhes bibliográficos
Main Authors: Pliotas, Christos, Ward, Richard, Branigan, Emma, Rasmussen, Akiko, Hagelueken, Gregor, Huang, Hexian, Black, Susan S., Booth, Ian R., Schiemann, Olav, Naismith, James H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479538/
https://ncbi.nlm.nih.gov/pubmed/23012406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202286109
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