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Nuclear transport receptor binding avidity triggers a self-healing collapse transition in FG-nucleoporin molecular brushes
Conformational changes at supramolecular interfaces are fundamentally coupled to binding activity, yet it remains a challenge to probe this relationship directly. Within the nuclear pore complex, this underlies how transport receptors known as karyopherins proceed through a tethered layer of intrins...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3479521/ https://ncbi.nlm.nih.gov/pubmed/23043112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208440109 |
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