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Structural basis for TetM-mediated tetracycline resistance
Ribosome protection proteins (RPPs) confer tetracycline resistance by binding to the ribosome and chasing the drug from its binding site. The current model for the mechanism of action of RPPs proposes that drug release is indirect and achieved via conformational changes within the drug-binding site...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3479509/ https://ncbi.nlm.nih.gov/pubmed/23027944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208037109 |
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