Aberrant expression of c-Jun in glioblastoma by internal ribosome entry site (IRES)-mediated translational activation

Although the protooncogene c-Jun plays a critical role in cell proliferation, cell death, and malignant transformation, DNA microarray screens have identified only a few human cancer types with aberrant expression of c-Jun. Here, we show that c-Jun accumulation is robustly elevated in human glioblas...

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Autors principals: Blau, Lior, Knirsh, Revital, Ben-Dror, Iris, Oren, Sivan, Kuphal, Silke, Hau, Peter, Proescholdt, Martin, Bosserhoff, Anja-Katrin, Vardimon, Lily
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479486/
https://ncbi.nlm.nih.gov/pubmed/23027969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203659109
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