Loss of E-Cadherin–mediated Cell–Cell Contacts Activates a Novel Mechanism for Up-Regulation of the Proto-Oncogene c-Jun

Loss of E-cadherin–mediated cell–cell contacts can elicit a signaling pathway that leads to acquisition of an invasive phenotype. Here, we show that at the receiving end of this pathway is the proto-oncogene c-Jun, a member of the activator protein-1 family of transcription factors that play a key r...

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Hlavní autoři: Knirsh, Revital, Ben-Dror, Iris, Spangler, Barbara, Matthews, Gideon D., Kuphal, Silke, Bosserhoff, Anja K., Vardimon, Lily
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663919/
https://ncbi.nlm.nih.gov/pubmed/19193763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-12-1196
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