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A framework for identification of actionable cancer genome dependencies in small cell lung cancer

Small cell lung cancer (SCLC) accounts for about 15% of all lung cancers. The prognosis of SCLC patients is devastating and no biologically targeted therapeutics are active in this tumor type. To develop a framework for development of specific SCLC-targeted drugs we conducted a combined genomic and...

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主要な著者: Sos, Martin L., Dietlein, Felix, Peifer, Martin, Schöttle, Jakob, Balke-Want, Hyatt, Müller, Christian, Koker, Mirjam, Richters, André, Heynck, Stefanie, Malchers, Florian, Heuckmann, Johannes M., Seidel, Danila, Eyers, Patrick A., Ullrich, Roland T., Antonchick, Andrey P., Vintonyak, Viktor V., Schneider, Peter M., Ninomiya, Takashi, Waldmann, Herbert, Büttner, Reinhard, Rauh, Daniel, Heukamp, Lukas C., Thomas, Roman K.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2012
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479457/
https://ncbi.nlm.nih.gov/pubmed/23035247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207310109
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