A framework for identification of actionable cancer genome dependencies in small cell lung cancer

Small cell lung cancer (SCLC) accounts for about 15% of all lung cancers. The prognosis of SCLC patients is devastating and no biologically targeted therapeutics are active in this tumor type. To develop a framework for development of specific SCLC-targeted drugs we conducted a combined genomic and...

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Detalhes bibliográficos
Main Authors: Sos, Martin L., Dietlein, Felix, Peifer, Martin, Schöttle, Jakob, Balke-Want, Hyatt, Müller, Christian, Koker, Mirjam, Richters, André, Heynck, Stefanie, Malchers, Florian, Heuckmann, Johannes M., Seidel, Danila, Eyers, Patrick A., Ullrich, Roland T., Antonchick, Andrey P., Vintonyak, Viktor V., Schneider, Peter M., Ninomiya, Takashi, Waldmann, Herbert, Büttner, Reinhard, Rauh, Daniel, Heukamp, Lukas C., Thomas, Roman K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479457/
https://ncbi.nlm.nih.gov/pubmed/23035247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207310109
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