Metabolic Signatures Uncover Distinct Targets in Molecular Subsets of Diffuse Large B-Cell Lymphoma

Molecular signatures have identified several subsets of Diffuse Large B-Cell Lymphoma (DLBCL) and rational targets within the B-cell receptor (BCR) signaling axis. The OxPhos-DLBCL subset, which harbors the signature of genes involved in mitochondrial metabolism, is insensitive to inhibition of BCR...

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Detalhes bibliográficos
Main Authors: Caro, Pilar, Kishan, Amar U., Norberg, Erik, Stanley, Illana, Chapuy, Bjoern, Ficarro, Scott B., Polak, Klaudia, Tondera, Daniel, Gounarides, John, Yin, Hong, Zhou, Feng, Green, Michael R., Chen, Linfeng, Monti, Stefano, Marto, Jarrod A., Shipp, Margaret A., Danial, Nika N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479446/
https://ncbi.nlm.nih.gov/pubmed/23079663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.08.014
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