Antibody Responses to Haemophilus influenzae Type b and Diphtheria Toxin Induced by Conjugates of Oligosaccharides of the Type b Capsule with the Nontoxic Protein CRM(197)

Oligosaccharides were made from Haemophilus influenzae type b capsular polysaccharide and conjugated to CRM(197) by reductive amination. Conjugates were made with a range of lengths and multiplicities of saccharide chains. All elicited a strongly enhanced anti-H. influenzae type b capsular polysacch...

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Bibliographic Details
Main Author: Anderson, Porter
Format: Artigo
Language:Inglês
Published: 1983
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC347931/
https://ncbi.nlm.nih.gov/pubmed/6600444
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