Quantitative mass spectrometry and PAR-CLIP to identify RNA-protein interactions

Systematic analysis of the RNA-protein interactome requires robust and scalable methods. We here show the combination of two completely orthogonal, generic techniques to identify RNA-protein interactions: PAR-CLIP reveals a collection of RNAs bound to a protein whereas SILAC-based RNA pull-downs ide...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Scheibe, Marion, Butter, Falk, Hafner, Markus, Tuschl, Thomas, Mann, Matthias
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
RNA
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479200/
https://ncbi.nlm.nih.gov/pubmed/22885304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks746
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky