Cockayne Syndrome group B protein interacts with TRF2 and regulates telomere length and stability

The majority of Cockayne syndrome (CS) patients carry a mutation in Cockayne Syndrome group B (CSB), a large nuclear protein implicated in DNA repair, transcription and chromatin remodeling. However, whether CSB may play a role in telomere metabolism has not yet been characterized. Here, we report t...

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Main Authors: Batenburg, Nicole L., Mitchell, Taylor R. H., Leach, Derrik M., Rainbow, Andrew J., Zhu, Xu-Dong
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2012
Teme:
Genome Integrity, Repair and Replication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479199/
https://ncbi.nlm.nih.gov/pubmed/22904069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks745
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