Catechol-O-Methyltransferase val158met Polymorphism Predicts Placebo Effect in Irritable Bowel Syndrome

Identifying patients who are potential placebo responders has major implications for clinical practice and trial design. Catechol-O-methyltransferase (COMT), an important enzyme in dopamine catabolism plays a key role in processes associated with the placebo effect such as reward, pain, memory and l...

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Autors principals: Hall, Kathryn T., Lembo, Anthony J., Kirsch, Irving, Ziogas, Dimitrios C., Douaiher, Jeffrey, Jensen, Karin B., Conboy, Lisa A., Kelley, John M., Kokkotou, Efi, Kaptchuk, Ted J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479140/
https://ncbi.nlm.nih.gov/pubmed/23110189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048135
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