Meningococcal Factor H Binding Protein fHbpd184 Polymorphism Influences Clinical Course of Meningococcal Meningitis

Factor H Binding protein (fHbp) is an important meningococcal virulence factor, enabling the meningococcus to evade the complement system, and a main target for vaccination. Recently, the structure of fHBP complexed with factor H (fH) was published. Two fHbp glutamic acids, E(283) and E(304), form s...

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Bibliografiske detaljer
Main Authors: Piet, Jurgen R., Brouwer, Matthijs C., Exley, Rachel, van der Veen, Stijn, van de Beek, Diederik, van der Ende, Arie
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479137/
https://ncbi.nlm.nih.gov/pubmed/23110143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047973
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