Inhibition of Cell Division Induced by External Guide Sequences (EGS Technology) Targeting ftsZ

EGS (external guide sequence) technology is a promising approach to designing new antibiotics. EGSs are short antisense oligoribonucleotides that induce RNase P-mediated cleavage of a target RNA by forming a precursor tRNA-like complex. The ftsZ mRNA secondary structure was modeled and EGSs compleme...

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Main Authors: Sala, Carol Davies, Soler-Bistué, Alfonso J. C., Korprapun, Leeann, Zorreguieta, Angeles, Tolmasky, Marcelo E.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479136/
https://ncbi.nlm.nih.gov/pubmed/23110089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047690
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