The Molecular Basis for Recognition of CD1d/α-Galactosylceramide by a Human Non-Vα24 T Cell Receptor

CD1d-mediated presentation of glycolipid antigens to T cells is capable of initiating powerful immune responses that can have a beneficial impact on many diseases. Molecular analyses have recently detailed the lipid antigen recognition strategies utilized by the invariant Vα24-Jα18 TCR rearrangement...

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Bibliographic Details
Main Authors: López-Sagaseta, Jacinto, Kung, Jennifer E., Savage, Paul B., Gumperz, Jenny, Adams, Erin J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479090/
https://ncbi.nlm.nih.gov/pubmed/23109910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001412
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