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Lysophospholipid presentation by CD1d and recognition by a human Natural Killer T-cell receptor

Invariant Natural Killer T (iNKT) cells use highly restricted αβ T cell receptors (TCRs) to probe the repertoire of lipids presented by CD1d molecules. Here, we describe our studies of lysophosphatidylcholine (LPC) presentation by human CD1d and its recognition by a native, LPC-specific iNKT TCR. Hu...

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Main Authors: López-Sagaseta, Jacinto, Sibener, Leah V, Kung, Jennifer E, Gumperz, Jenny, Adams, Erin J
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343337/
https://ncbi.nlm.nih.gov/pubmed/22395072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.54
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