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Antineoplastic Effects of Decitabine, an Inhibitor of DNA Promoter Methylation, in Adrenocortical Carcinoma Cells
HYPOTHESES: Decitabine recovers expression of silenced genes on chromosome 11q13 and has antineoplastic effects in adrenocortical carcinoma (ACC) cells. DESIGN: NCI-H295R cells were treated with decitabine (0.1–1.0μM) over 5 days. Cells were evaluated at 24-hour intervals for the effects of decitabi...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3478887/ https://ncbi.nlm.nih.gov/pubmed/20231622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archsurg.2009.292 |
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