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EP1 DISRUPTION ATTENUATES END-ORGAN DAMAGE IN A MOUSE MODEL OF HYPERTENSION
PGE(2) is a major prostanoid found in the kidney and vasculature contributing to the regulation of blood pressure. The PGE(2) receptor EP1 has been shown to contribute to hypertension by mediating angiotensin II-dependent vasoconstriction, although its precise role is incompletely characterized. Dis...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3478772/ https://ncbi.nlm.nih.gov/pubmed/23006735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.112.199026 |
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