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EP1 DISRUPTION ATTENUATES END-ORGAN DAMAGE IN A MOUSE MODEL OF HYPERTENSION

PGE(2) is a major prostanoid found in the kidney and vasculature contributing to the regulation of blood pressure. The PGE(2) receptor EP1 has been shown to contribute to hypertension by mediating angiotensin II-dependent vasoconstriction, although its precise role is incompletely characterized. Dis...

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Detalhes bibliográficos
Main Authors: Swan, Christina E., Boyd, Kelli L., Harris, Raymond C., Zent, Roy, Breyer, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478772/
https://ncbi.nlm.nih.gov/pubmed/23006735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.112.199026
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