Mouse EP3 α, β, and γ Receptor Variants Reduce Tumor Cell Proliferation and Tumorigenesis in Vivo

Prostaglandin E(2), which exerts its functions by binding to four G protein-coupled receptors (EP1-4), is implicated in tumorigenesis. Among the four E-prostanoid (EP) receptors, EP3 is unique in that it exists as alternatively spliced variants, characterized by differences in the cytoplasmic C-term...

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Detalhes bibliográficos
Main Authors: Macias-Perez, Ines M., Zent, Roy, Carmosino, Monica, Breyer, Matthew D., Breyer, Richard M., Pozzi, Ambra
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335350/
https://ncbi.nlm.nih.gov/pubmed/18230618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800105200
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