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Thiadiazolidinones: A New Class of Alanine Racemase Inhibitors with Antimicrobial Activity against Methicillin- Resistant S. aureus

Methicillin-resistant Staphylococcus aureus (MRSA) is a human pathogen and a major cause of hospital-acquired infections. New antibacterial agents that have not been compromised by bacterial resistance are needed to treat MRSA-related infections. We chose the S. aureus cell wall synthesis enzyme, al...

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Detalhes bibliográficos
Principais autores: Ciustea, Mihai, Mootien, Sara, Rosato, Adriana E., Perez, Oriana, Cirillo, Pier, Yeung, Kacheong R., Ledizet, Michel, Cynamon, Michael H., Aristoff, Paul A., Koski, Raymond A., Kaplan, Paul A., Anthony, Karen G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478562/
https://ncbi.nlm.nih.gov/pubmed/22146584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.11.021
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