A Novel Allosteric Inhibitor of Macrophage Migration Inhibitory Factor (MIF)

Macrophage migration inhibitory factor (MIF) is a catalytic cytokine and an upstream mediator of the inflammatory pathway. MIF has broad regulatory properties, dysregulation of which has been implicated in the pathology of multiple immunological diseases. Inhibition of MIF activity with small molecu...

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Detalhes bibliográficos
Main Authors: Bai, Fengwei, Asojo, Oluwatoyin A., Cirillo, Pier, Ciustea, Mihai, Ledizet, Michel, Aristoff, Paul A., Leng, Lin, Koski, Raymond A., Powell, Thomas J., Bucala, Richard, Anthony, Karen G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436310/
https://ncbi.nlm.nih.gov/pubmed/22782901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.385583
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