Evidence of Gene-Gene Interaction and Age-at-Diagnosis Effects in Type 1 Diabetes

The common genetic loci that independently influence the risk of type 1 diabetes have largely been determined. Their interactions with age-at-diagnosis of type 1 diabetes, sex, or the major susceptibility locus, HLA class II, remain mostly unexplored. A large collection of more than 14,866 type 1 di...

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Autori principali: Howson, Joanna M.M., Cooper, Jason D., Smyth, Deborah J., Walker, Neil M., Stevens, Helen, She, Jin-Xiong, Eisenbarth, George S., Rewers, Marian, Todd, John A., Akolkar, Beena, Concannon, Patrick, Erlich, Henry A., Julier, Cécile, Morahan, Grant, Nerup, Jørn, Nierras, Concepcion, Pociot, Flemming, Rich, Stephen S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2012
Soggetti:
Genetics/Genomes/Proteomics/Metabolomics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478521/
https://ncbi.nlm.nih.gov/pubmed/22891215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1694
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