Tests for Genetic Interactions in Type 1 Diabetes: Linkage and Stratification Analyses of 4,422 Affected Sib-Pairs

OBJECTIVE: Interactions between genetic and environmental factors lead to immune dysregulation causing type 1 diabetes and other autoimmune disorders. Recently, many common genetic variants have been associated with type 1 diabetes risk, but each has modest individual effects. Familial clustering of...

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Detalhes bibliográficos
Main Authors: Morahan, Grant, Mehta, Munish, James, Ian, Chen, Wei-Min, Akolkar, Beena, Erlich, Henry A., Hilner, Joan E., Julier, Cécile, Nerup, Jørn, Nierras, Concepcion, Pociot, Flemming, Todd, John A., Rich, Stephen S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2011
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046821/
https://ncbi.nlm.nih.gov/pubmed/21266329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1195
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