Deficiency in the nuclear factor E2-related factor 2 renders pancreatic β-cells vulnerable to arsenic-induced cell damage

Chronic human exposure to inorganic arsenic (iAs), a potent environmental oxidative stressor, is associated with increased prevalence of Type 2 diabetes, where impairment of pancreatic β-cell function is a key pathogenic factor. Nuclear factor E2-related factor 2 (Nrf2) is a central transcription fa...

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Hlavní autoři: Yang, Bei, Fu, Jingqi, Zheng, Hongzhi, Xue, Peng, Yarborough, Kathy, Woods, Courtney G, Hou, Yongyong, Zhang, Qiang, Andersen, Melvin E., Pi, Jingbo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478490/
https://ncbi.nlm.nih.gov/pubmed/23000044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2012.09.012
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